Publications

• Celeste D. Rosencrance, Haneen N. Ammouri, Qi Yu, Tiffany Ge, Emily J. Rendleman, Stacy A. Marshall, Kyle P. Eagen. Chromatin Hyperacetylation Impacts Chromosome Folding by Forming a Nuclear Subcompartment. Molecular Cell (2020) 78, 112-126. Full Text
  • Highlighted in Nature Reviews Molecular Cell Biology
• Celestia Fang*, Zhenjia Wang*, Cuijuan Han, Stephanie L. Safgren, Kathryn A. Helmin, Emmalee R. Adelman, Valentina Serafin, Giuseppe Basso, Kyle P. Eagen, Alexandre Gaspar-Maia, Maria E. Figueroa, Benjamin D. Singer, Aakrosh Ratan, Panagiotis Ntziachristos†, Chongzhi Zang†. Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation. Genome Biology (2020) 21, 247. Full Text. *Equal contributions †Corresponding author
• Tiffany Ge*, Celeste D. Rosencrance*, Kyle P. Eagen. Contact Mapping to Unravel Chromosome Folding. Trends in Biochemical Sciences (2019) 44, 98-99. Full Text *Equal contributions
• ​Kyle P. Eagen. Principles of Chromosome Architecture Revealed by Hi-C. Trends in Biochemical Sciences (2018) 43, 469-478. Full Text
  • Cover Article​
  • Best of Trends Series: Best and most downloaded review published in Trends in Biochemical Sciences in 2018
  • Highlighted in F1000 Prime
• Kyle P. Eagen*, Erez Lieberman Aiden, Roger D. Kornberg*. Polycomb-Mediated Chromatin Loops Revealed by a Sub-kilobase Resolution Chromatin Interaction Map. Proceedings of the National Academy of Sciences of the United States of America (2017) 114, 8764-8769. Full Text *Corresponding author
  • Highlighted in F1000 Prime.
• Shigeki Nagai, Ralph E. Davis, Pierre Jean Mattei, Kyle P. Eagen, Roger D. Kornberg. Chromatin Potentiates Transcription. Proceedings of the National Academy of Sciences of the United States of America (2017) 114, 1536-1541. Full Text
• Kyle P. Eagen, Tom A. Hartl, Roger D. Kornberg. Stable Chromosome Condensation Revealed by Chromosome Conformation Capture. Cell (2015) 163, 934-946. Full Text
  • Highlighted in Nature Reviews Molecular Cell Biology, Nature Reviews Genetics, and F1000 Prime.
• Ryan W. Lewis, John Mabry, Jason G. Polisar, Kyle P. Eagen, Bruce Ganem, George P. Hess. Dihydropyrimidinone Positive Modulation of Delta Subunit-containing GABAA Receptors, Including an Epilepsy-linked Mutant Variant. Biochemistry (2010) 49, 4841-4851. Full Text
• Brian A. Kelch, Kyle P. Eagen, F. Pinar Erciyas, Elizabeth L. Humphris, Adam R. Thomason, Shinji Mitsuiki, David A. Agard. Structural and Mechanistic Exploration of Acid Resistance: Kinetic Stability Facilitates Evolution of Extremophilic Behavior. Journal of Molecular Biology (2007) 368, 870-883. Full Text
  • ​Cover Article